Sex differences in cardiac remodelling in ischaemic cardiomyopathy and functional mitral regurgitation: impact on prognosis.

ABSTRACT:

Aims

Sex differences in prognosis of functional mitral regurgitation (FMR) associated with ischaemic cardiomyopathy (ICM) demonstrate the need to identify sex differences in cardiac remodelling. This study aimed to characterize sex differences in cardiac remodelling associated with FMR in the setting of ICM, sex interactions with cardiac remodelling and FMR severity, and predictors of all-cause mortality or heart transplantation using cardiac magnetic resonance (CMR) imaging.

Methods and results

Consecutive patients with ICM referred to CMR between 2002 and 2017 were reviewed. Eligible 790 patients [mean age: 62.0 (standard deviation = 11.2] years and 24.7% females] were evaluated over a median follow-up of 5.8 years. There were 773 subjects with complete data for survival a

SUBMITTER: Kocyigit Burunkaya D 

PROVIDER: S-EPMC11920871 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature