Epidemiologic profile of community-acquired <i>Clostridioides difficile</i> infections: a systematic review and meta-analysis.

ABSTRACT: Clostridiodes difficile's epidemiology has evolved over the past decades, being recognized as an important cause of disease in the community setting. Even so, there has been heterogeneity in the reports of CA-CDI. Therefore, the aim of this study was to assess the epidemiologic profile of CA-CDI.This systematic review and meta-analysis were conducted according to PRISMA checklist and Cochrane guidelines (CRD42023451134). Literature search was performed by an experienced librarian from inception to April 2023, searching in databases like MEDLINE, Scopus, Web of Science, EMBASE, CCRCC, CDSR, and ClinicalTrials. Observational studies that reported prevalence, incidence of CA-CDI, or indicators to calculate them were included. Pool analysis was performed using a binomial-normal model vi

SUBMITTER: Alvarez-Villalobos NA 

PROVIDER: S-EPMC11920921 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature