Local-region treatment comparison following conversion therapy of hepatocellular carcinoma: a period and age-dependent analysis.

ABSTRACT:

Background

Transarterial chemoembolization (TACE) is a potential conversion therapeutic strategy for unresectable hepatocellular carcinoma (uHCC). However, therapeutic options following conversion therapy are still controversial.

Objectives

This study aimed to compare the efficacy and safety of surgical resection (SR) and microwave ablation (MWA) after TACE conversion therapy for uHCC.

Design

A retrospective, multi-institutional study.

Methods

From June 2008 to October 2022, 8842 consecutive uHCC patients underwent initial TACE at 15 hospitals were identified. Among them, 1348 eligible patients who received TACE conversion therapy were included. The propensity score matching (PSM) was applied to reduce selection bias. To explore the effect of age on conversion

SUBMITTER: Hu J 

PROVIDER: S-EPMC11921006 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature