Light-Driven Photobiocatalytic Oxyfunctionalization in a Continuous Reactor System without External Oxygen Supply.

ABSTRACT: Oxygenases catalyze C-H oxyfunctionalization under mild reaction conditions and often display outstanding selectivity. However, their utilization is hampered by the difficulty of transporting oxygen across the gas-liquid interface, which is particularly problematic for continuous reactor systems and can only be alleviated by high pressure or the use of complex oxygen-permeable materials. Herein, oxygen is directly released into the medium by the phototrophic cyanobacterium Synechocystis sp. PCC 6803 expressing the genes of a Baeyer-Villiger Monooxygenase from Burkholderia xenovorans to drive the oxidation of cyclohexanone for the production of the polymer precursor, ε-caprolactone. The rates at which photosynthetic oxygen can solely drive the oxidation were determined by perf

SUBMITTER: Malihan-Yap L 

PROVIDER: S-EPMC11921032 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature