Patient preferences for adjuvant therapy in renal cell carcinoma: a discrete-choice experiment.

ABSTRACT:

Introduction

To quantify patients' preferences for adjuvant renal cell carcinoma (RCC) treatments.

Patients and methods

Preferences were elicited using a discrete-choice experiment requiring RCC patients to choose between 2 hypothetical treatments. Data were analyzed using random-parameters logit and latent-class models.

Results

Patients (n = 250) preferred treatments that increase disease-free and overall survival (OS), are taken less frequently, require no concomitant medication, have a shorter duration, and have lower side-effect risks. The analyses also highlighted their willingness to make tradeoffs between these benefits and risks. Patients were generally tolerant of increases in the risks of treatment-related severe diarrhea, dizziness, and fatigue and w

SUBMITTER: Calhoun SR 

PROVIDER: S-EPMC11921160 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature