Survival analysis comparing bladder preservation techniques in octogenarians with muscle-invasive bladder cancer.

ABSTRACT:

Background

The gold standard treatment for localized muscle-invasive bladder cancer (MIBC) is neoadjuvant chemotherapy with radical cystectomy (RC). Guidelines suggest concurrent chemoradiation (CRT) could be considered as an alternative, and partial cystectomy (PC) may be considered in carefully selected individuals. The bladder preservation strategies are gaining popularity, and due to the concerns about morbidity associated with RC and limited life expectancy, the octogenarian population is exploring strategies that help preserve bladder function. Hence, it is crucial to understand the outcome of various bladder preservation strategies. Using the National Cancer Database (NCDB), we compared the overall survival (OS) of octogenarians treated with PC and CRT.

Methods

We ret

SUBMITTER: Avudaiappan AP 

PROVIDER: S-EPMC11921227 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature