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A current knowledge of the undifferentiated carcinoma of the pancreas with osteoclast-like giant cells: a narrative review.


ABSTRACT:

Background and objective

Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (UCOGC) is a rare variant of malignant pancreatic tumor. There is still no standardized treatment for this uncommon subtype, as surgical resection with lymphadenectomy is the only potentially curative treatment so far. In this paper, we describe the current knowledge of this very rare specific subtype of pancreatic cancer (PC) as a narrative review.

Methods

For this review, we did not specify the time range of studies referred to due to limited data availability. Our inclusion criteria comprised previous studies, which specifically focused on the rare UCOGC subtype of PC as a confirmed histopathology, either pure or present together with other subtypes. We disregarded the stu

SUBMITTER: Gayibov E 

PROVIDER: S-EPMC11921273 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature