A prospective clinical study of allergy progression in identical and fraternal twin pairs of children.

ABSTRACT:

Background

Understanding the factors leading to the development of allergic disease is a critical area of research. We studied the development of allergic disease in identical and fraternal twins to identify potential differences in environment versus genetic factors.

Methods

Twins aged up to 4 years were selected for inclusion in this long-term follow-up study. Regular questionnaire results, allergen levels, and other indicators were examined.

Results

A total of 80 twins were included in this study. Over time, the incidence of atopic dermatitis (AD) decreased, and the incidence of rhinitis and wheezing increased. The incidence of AD, rhinitis, and food allergy was significantly higher in identical twins than fraternal twins. The consistency of positive inhaled allerg

SUBMITTER: Wang J 

PROVIDER: S-EPMC11921276 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature