Risk factors for postoperative pulmonary complications in non-adenocarcinoma non-small cell lung cancer patients undergoing surgery after neoadjuvant therapy.

ABSTRACT:

Background

Neoadjuvant therapy followed by surgery is the recommended treatment for patients with locally advanced lung cancer. No studies have examined the risk factors of postoperative pulmonary complications (PPCs) in this group of patients. The addition of immune checkpoint inhibitors (ICIs) can improve the efficacy of neoadjuvant therapy; however, it is unknown whether ICIs will also increase the PPC incidence. Thus, we conducted this study to identify the predictors of PPCs.

Methods

We reviewed the database of Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University. Patients with non-adenocarcinoma non-small cell lung cancer (non-ADC NSCLC) who underwent surgery after neoadjuvant therapy were included. The clinical information was collected, the PPCs and mor

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11921298 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature