Peripheral blood cytokine expression levels and their clinical significance in children with influenza.

ABSTRACT:

Background

Cytokine levels in the peripheral blood of children infected with the influenza A virus are significantly associated with disease diagnosis and severity. This study aimed to investigate the correlation between the expression levels of six cytokines in the peripheral blood of pediatric patients with influenza and the diagnosis and severity of their condition.

Methods

The levels of six cytokines were measured using a flow cytometric microsphere array. Statistical analysis was performed using IBM SPSS Statistics 26.0 to compare differences between the groups, with a P value of less than 0.05 considered statistically significant.

Results

Univariate analysis showed that the levels of interferon alpha-2 (IFN-α2), monocyte chemoattractant protein-1 (MCP-1), interl

SUBMITTER: Zou Y 

PROVIDER: S-EPMC11921373 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature