Systemic treatment for recurrence of hepatocellular carcinoma after liver transplantation: a case report.

ABSTRACT:

Background

Liver transplantation (LT) is considered the optimal treatment approach for patients with cirrhosis progressing to hepatocellular carcinoma (HCC). LT not only allows for complete removal of tumors from the liver but also potentially eliminates cirrhosis. However, recurrence of HCC after LT remains a significant issue, with recurrence rates ranging from 8% to 20%. The median time to recurrence is 14 months, and the median survival after recurrence is 12.2 months. We present the first case of long-term remission following hepatic arterial infusion chemotherapy (HAIC) combined with targeted therapy in a patient with multifocal recurrence and distant metastasis of HCC after LT.

Case description

A 62-year-old male experienced recurrence of HCC after LT, with metastases

SUBMITTER: Deng M 

PROVIDER: S-EPMC11921418 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature