Clinicopathological Characteristics and Outcomes of Lupus Nephritis Patients With Thrombocytopenia: A Single-Center Retrospective Study.

ABSTRACT:

Objectives

The objective of this study is to analyze and summarize the clinical characteristics and prognosis of lupus nephritis (LN) patients with thrombocytopenia and to improve the cognition of the disease.

Methods

896 LN patients were enrolled in this study and their clinical and pathological data were collected and analyzed. The primary end point was mortality. The secondary end point was adverse renal outcomes, defined as doubling of the baseline serum creatinine or end-stage renal diseases. Cox regression model was used to analyze the risk factors of mortality or renal events in LN with and without thrombocytopenia.

Results

Among 896 LN patients, 70 (7.8%) were diagnosed with thrombocytopenia. LN patients with thrombocytopenia had lower estimated glomerular fil

SUBMITTER: Diao H 

PROVIDER: S-EPMC11921463 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature