Association between exposure to organophosphate esters and cognitive function in older adults in the United States: NHANES 2011-2014.

ABSTRACT:

Background

Organophosphate esters (OPEs) are widely used as an alternative to the brominated flame retardant polybrominated diphenyl ethers. The effects of OPEs on the cognitive abilities of older adults remain unclear.

Methods

A cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey 2011-2014. Cognitive function was assessed using the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) word learning test, the CERAD word recall test, the Animal Fluency Test (AFT), and the Digit Symbol Substitution Test (DSST). OPE metabolites with detection rates above 50% were included in the study. Weighted multiple linear regression, weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) models

SUBMITTER: Jiang B 

PROVIDER: S-EPMC11921510 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature