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ABSTRACT: Background
The role of biological factors such as foetal haemoglobin in modifying the severity of Sickle Cell Anaemia (SCA) has been extensively investigated. However, the phenotypic variability of SCA cannot be explained by genetic factors alone. Hence, the need to determine other correlates of SCA severity such as perceived stress and social support.Methods
This was a hospital-based cross-sectional study involving 60 participants aged 8-17 years selected using simple random sampling technique. Standard rating scales (i.e., SCA scoring system, perceived stress scale, and child and adolescent social support scale) were used to assess the severity of SCA, perceived stress and social support, respectively. Foetal haemoglobin (HbF) was estimated using high performance liquid c
SUBMITTER: Onu NN
PROVIDER: S-EPMC11921521 | biostudies-literature | 2025 Mar
REPOSITORIES: biostudies-literature