Association between gestational weight change trajectories and perinatal outcomes in twin pregnancies in China.

ABSTRACT:

Objective

This study aimed to identify gestational weight change trajectories and examine their association with perinatal outcomes.

Methods

Prenatal and delivery records of 3393 twin pregnancies were obtained from the China-US Collaborative Project for Neural Tube Defects Prevention, a large population-based cohort study. Generalized gestational weight gain (GWG) was calculated by dividing the total GWG by the length of gestation in weeks and multiplying by 37 weeks. Latent class growth modeling (LCGM) was used to identify GWG patterns. Multivariable logistic regression and generalized estimating equations (GEE) were used to analyze the associations between GWG trajectories and perinatal outcomes. The included adverse perinatal outcomes were preterm birth, low birth weight

SUBMITTER: Li M 

PROVIDER: S-EPMC11921534 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature