Clinical features and current management experience in Gorham-Stout disease: a systematic review.

ABSTRACT:

Background

Gorham-Stout disease (GSD) is a rare complex lymphatic malformation. Since its initial description in 1838, only approximately 400 patients have been documented. There is currently no consensus on the diagnostic criteria or treatment options for GSD. The objective of this study was to review the clinical characteristics of patients with GSD and determine the current diagnostic and treatment models.

Methods

A comprehensive search of the PubMed, Web of Science, Embase, and Cochrane Library databases was conducted to identify all relevant literature on GSD published over the decade from 2013 to 2023. The clinical information extracted from these publications was analyzed.

Results

A total of 206 patients with GSD were included in the study, comprising 119 males

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC11921740 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature