The prevalence of nonalcoholic fatty liver disease in people living with HIV: a systematic review and meta-analysis.

ABSTRACT:

Background

Owing to long-term antiretroviral therapy (ART), the incidence of non-HIV-related chronic diseases is increasing, and liver disease is the leading cause of increased AIDS mortality. Moreover, the prevalence of NAFLD and liver fibrosis has been reported to vary widely across regions and studies. There is no precise description of the trend and characteristics of NAFLD in PLWH. Here, we aimed to explore the prevalence and outcomes of NAFLD in people living with HIV (PLWH).

Methods

The PubMed, Web of Science, Embase, and Cochrane Library databases were searched on August 15, 2023, for studies that evaluated the prevalence of NAFLD or liver fibrosis among PLWH. The meta-synthesized effects of NAFLD and liver fibrosis were the primary outcomes, and potential moderators

SUBMITTER: Wei J 

PROVIDER: S-EPMC11921747 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature