Longitudinal registration of T₁-weighted breast MRI: A registration algorithm (FLIRE) and clinical application.

ABSTRACT:

Purpose

MRI is commonly used to aid breast cancer diagnosis and treatment evaluation. For patients with breast cancer, neoadjuvant chemotherapy aims to reduce the tumor size and extent of surgery necessary. The current clinical standard to measure breast tumor response on MRI uses the longest tumor diameter. Radiologists also account for other tissue properties including tumor contrast or pharmacokinetics in their assessment. Accurate longitudinal image registration of breast tissue is critical to properly compare response to treatment at different timepoints.

Methods

In this study, a deformable Fast Longitudinal Image Registration (FLIRE) algorithm was optimized for breast tissue. FLIRE was then compared to the publicly available software packages with high accuracy (DRAMMS

SUBMITTER: Tong MW 

PROVIDER: S-EPMC11921785 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature