Poor Treatment Response in Panic Disorder Patients with Suicide Attempts and Their Symptom Network Characteristics.

ABSTRACT:

Background

Panic disorder (PD) is associated with suicidality. Depression has been suggested as a link between PD and suicide; however, this remains controversial. Comprehensive research on the history of suicide attempt (SA) in patients with PD is scarce. We investigated the clinical characteristics of SA in patients with PD using PD-related assessments and network approaches.

Methods

A total of 1151 participants were enrolled, including 755 patients with PD (97 with SA (PD+SA) and 658 without SA (PD-SA)) and 396 healthy controls. The Scale for Suicide Ideation and Panic Disorder Severity, Anxiety Sensitivity Inventory, and other PD-related measures were also administered. We compared symptom severity and analyzed the pharmacological treatment response in patients with PD w

SUBMITTER: Kim HJ 

PROVIDER: S-EPMC11921835 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature