Effects of calcium supplementation on the prevention of preeclampsia: an umbrella review of systematic reviews and meta-analyses.

ABSTRACT:

Background

Preeclampsia is the leading cause of maternal and fetal morbidity and mortality. Calcium supplementation has been considered a potential intervention to reduce the risk of preeclampsia. This umbrella review aims to summarize the effects of calcium supplementation in the prevention of preeclampsia based on existing systematic reviews and meta-analyses studies.

Methods

A systematic search of electronic databases, such as MEDLINE, Web of Science, SCOPUS, and the Cochrane Library, was conducted from inception to 30 December 2023. The methodological quality of the included studies was assessed using the revised version of the Assessing the Methodological Quality of Systematic Reviews (AMSTAR 2) tool. A random-effects model was used to estimate the effect of calcium sup

SUBMITTER: Kumsa H 

PROVIDER: S-EPMC11922079 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature