Guillain-Barre syndrome after the Zika epidemic in Colombia: A multicenter, matched case-control study.

ABSTRACT:

Background

Zika produced the highest increase in the incidence of Guillain-Barré syndrome (GBS) in Latin America in the last decade. The Neuroinfections Emerging in the Americas Study (NEAS) was established in 2016 to investigate the association of emerging infectious disorders with GBS in Colombia. The present study assessed the role of preceding infections, including arboviruses and other pathogens, as risk factors for GBS.

Methods

A case-control study was conducted prospectively between June 2016 and December 2019 in 5 Colombian cities. We recruited newly diagnosed patients with GBS and a house control plus an age and season-matched-hospital control per case. Clinical information, blood, CSF, and urine samples were used to diagnose bacterial and viral infections. Anti-gly

SUBMITTER: Osorio L 

PROVIDER: S-EPMC11922255 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature