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Endoscopic submucosal dissection for proximal colonic lesions: An effective therapeutic option.


ABSTRACT:

Background and study aims

Due to the greater risks of adverse events (AEs) and the lower rate of submucosal invasive cancer (SMIC), large proximal colonic polyps are frequently treated by piecemeal endoscopic mucosal resection (EMR) in the West. However, this implies the risk of surgery to radicalize non-curative endoscopic resection in case of early colorectal cancer (CRC). We evaluated procedure outcomes in patients undergoing ESD for proximal colonic lesions at risk of SMIC.

Patients and methods

All consecutive patients with lesions at risk of SMIC proximal to splenic flexure referred for ESD at a tertiary center were prospectively included from 2019 to 2021. En bloc, R0, and curative resection rates were primary outcomes, while length of hospitalization, AEs, need for su

SUBMITTER: Alfarone L 

PROVIDER: S-EPMC11922310 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature