Prognostic factors of brain metastasis and subsequent survival in breast cancer patients: An 11-year, single-center, retrospective study.

ABSTRACT: Female breast cancer is among the most prevalent cancers globally, often metastasizing to the brain. Despite advancements in treatment, brain metastasis incidence is rising, with a poor prognosis. Moreover, limited data exist on how breast cancer subtypes and patient characteristics impact survival. This study aimed to investigate prognostic factors affecting breast cancer patients with brain metastasis. We retrospectively reviewed 131 breast cancer patients with brain metastasis diagnosed at a single institution between 2010 and 2020. Demographic, clinical, pathological, and radiographic variables were analyzed. The median interval between breast cancer diagnosis and brain metastasis was 27 months. Patients diagnosed with a higher stage of breast cancer (median survival: stage 1: 97.2 mon

SUBMITTER: Lee GH 

PROVIDER: S-EPMC11922408 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature