Characterization of Macular Fundus Autofluorescence Changes in Patients with Retinitis Pigmentosa.

ABSTRACT:

Introduction

The aim of this study was to characterized fundus autofluorescence (AF) changes that occur in the macula of patients with retinitis pigmentosa (RP).

Methods

We conducted a case series on 99 patients with RP. Features seen on fundus AF images were evaluated, organized into a grading scheme, and correlated with ellipsoid zone (EZ) width. Patterns of AF changes occurring in the macula and correlation with EZ width.

Results

Four primary fundus AF phenotypes were identified: (1) hyperAF arc, (2) hyperAF ring, (3) hyperAF ring with abnormal hyperAF within the ring, and (4) central hyperAF. The second phenotype was most common and had 3 subgroups, hyperAF rings within the macula, those extending outside the macula, and incomplete rings. HyperAF rings were also c

SUBMITTER: Khan MJ 

PROVIDER: S-EPMC11922654 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature