Global burden, trends and inequalities of maternal hypertensive disorders among reproductive-age women of advanced maternal age, 1990-2021: a population-based study.

ABSTRACT:

Background

Maternal hypertensive disorders (MHD) are leading causes of maternal morbidity and mortality worldwide, particularly among reproductive-age women of advanced maternal age (AMA), representing a significant global public health challenge.

Objective

This study aimed to analyze the global trends, inequalities, and disparities in the burden of MHD among reproductive-age AMA women from 1990 to 2021.

Methods

We conducted a population-based study using data from the Global Burden of Disease (GBD) 2021 study, covering 204 countries and territories. The study included women aged 35-49 years with hypertensive disorders during pregnancy. We assessed age-standardized incidence rate (ASIR) and age-standardized death rate (ASDR) of MHD among reproductive-age AMA women. Te

SUBMITTER: Zhao X 

PROVIDER: S-EPMC11922729 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature