Identification and phylogenetic characterization of novel hunnivirus recombinant strains in cattle from Guangxi, China.

ABSTRACT:

Introduction

Hunnivirus (HuV), a member of the Picornaviridae family, is a single-stranded RNA virus associated with gastrointestinal issues in animals and poses potential zoonotic risks. While HuV has been detected in various animals, its prevalence and genetic characteristics in cattle remain poorly understood.

Methods

From 2021 to 2023, we collected 1,017 fecal samples from cattle across Guangxi, China, and analyzed them for HuV using RT-PCR. Phylogenetic and sequence analyses were conducted to assess the virus's genetic diversity and potential recombination events. Additionally, five HuV-positive samples were selected for whole-genome amplification and sequencing.

Results

The overall prevalence of HuV was 3.05%, with significantly higher detection rates in diarrhe

SUBMITTER: Zhang G 

PROVIDER: S-EPMC11922853 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature