Smart green spectrophotometric estimation and content uniformity testing of chlorphenoxamine HCl and caffeine in bulk forms and combined pharmaceutical formulation.

ABSTRACT: Chlorphenoxamine hydrochloride is a chemical that has attracted interest because of its notable anti-histaminic and anti-cholinergic characteristics. Moreover, it has been recognized as a highly efficient tool in the fight against several lethal viral diseases, such as Severe Acute Respiratory Syndrome Coronavirus. In this study, five efficient and straightforward univariate spectrophotometric approaches are proposed for accurately measuring the quantities of Caffeine and Chlorphenoxamine HCl in bulk forms and combined pharmaceutical formulations. Notably, these methods based on an advanced approach using the factorized response spectrum and not require any initial processing.They have been classified into three spectrophotometric platform windows. The study of Window I focuses on absorpti

SUBMITTER: Ashraf A 

PROVIDER: S-EPMC11923055 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature