ZIF-67 decorated with silica nanoparticles and graphene oxide nanosheets composite modified electrode for simultaneous determination of paracetamol and diclofenac.

ABSTRACT: In this work, a novel nanocomposite containing zeolitic imidazolate framework-67 decorated silica nanoparticles/graphene oxide nanosheets (ZIF-67/SiO₂NPs/GONs) was synthesized and used for the fabrication of the modified glassy carbon electrode for individual and simultaneous electrodetermination of paracetamol (PAR) and diclofenac (DIC) at trace levels. Structural and morphological characterization of the nanocomposite were carried out using suitable techniques. The modified electrode; ZIF-67/SiO₂NPs/GONs/GCE, exhibited excellent electrocatalytic activities toward the oxidation of PAR and DIC than the bare GCE, GONs/GCE, SiO₂NPs/GONs/GCE and ZIF-67/GCE. Through using differential pulse voltammetry, the individual and simultaneous determination of PAR and D

SUBMITTER: Habibi B 

PROVIDER: S-EPMC11923285 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature