Optimising fluid therapy during venoarterial extracorporeal membrane oxygenation: current evidence and future directions.

ABSTRACT: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) offers an immediate and effective mechanical cardio-circulatory support for critically ill patients with refractory cardiogenic shock or selected refractory cardiac arrest. As fluid therapy is routinely performed as a component of initial hemodynamic resuscitation of ECMO supported patients, this narrative review intends to summarize the rationale and the evidence on the fluid resuscitation strategy in terms of fluid type and dosing, the impact of fluid balance on outcomes and fluid responsiveness assessment in VA-ECMO patients. Several observational studies have shown a deleterious impact of positive fluid balance on survival and renal outcomes. With regard to the type of crystalloids, further studies are needed to evaluate the sa

SUBMITTER: Jendoubi A 

PROVIDER: S-EPMC11923310 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature