Simultaneous Multiclass Analysis of Cyanotoxins in Cyanobacterial Samples Using Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry.

ABSTRACT: The proliferation of cyanobacteria can result in algal blooms, which may cause environmental and biological harm due to the production and release of secondary metabolites, or cyanotoxins, into the affected waterway. Cyanobacteria can produce multiple classes of cyanotoxins; therefore, to understand the full toxic load of algal blooms, it is necessary to perform analyses that quantify each class. These classes are generally monitored individually due to the challenges associated with the differing physicochemical properties of the cyanotoxins. Hydrophilic interaction liquid chromatography (HILIC) is a form of chromatography capable of retaining multiple classes of cyanotoxins that differ in physicochemical properties. Here an HILIC-MS/MS method was developed and validated to detect 3 micro

SUBMITTER: Bergin R 

PROVIDER: S-EPMC11923511 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature