<i>Paeonia suffruticosa</i> Andrews root extract ameliorates photoaging via regulating IRS1/PI3K/FOXO pathway.

ABSTRACT:

Introduction

The root of Paeonia suffruticosa Andrews (P. suffruticosa Andr.), is a traditional Chinese medicine. Numerous studies have shown that it possesses anti-inflammatory, antioxidant, and anti-aging effects due to its rich content of bioactive compounds such as polyphenols and paeonol. Thus, it finds extensively applied in the fields of medicine and cosmetics. However, there are few reports on the photoprotective effects of P. suffruticosa Andr. root bark, this study aims to investigate its research in this area.

Methods

This study utilized P. suffruticosa Andr. root bark sourced from Kunming, Yunnan Province, China. The P. suffruticosa Andr. root extract (PSAE) was obtained using AB-8 resin. The photoprotective effect of PSAE was a

SUBMITTER: Liu J 

PROVIDER: S-EPMC11923548 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature