Social determinants of health and risk of dementia among older men and women: A 12-year cohort study in Australia.

ABSTRACT:

Introduction

Social determinants of health (SDH) are recognized as contributing factors to cognitive disorders, but their collective influence on dementia risk remains unclear.

Methods

A gender-disaggregated analysis was conducted on 12,896 community-dwelling older Australians (mean ± SD age: 75.2 ± 4.3 years; 54% women) without major cognitive impairment upon enrollment. Latent class analysis identified clusters from 72 SDH (70 individual-level and 2 neighborhood-level), while Cox proportional hazards regression estimated dementia risk over 12 years (median: 8.4) follow-up.

Results

Four clusters were identified: least disadvantaged (Class 1: 31.5% men; 30.6% women), most disadvantaged (Class 2: 20.2% men; 19.4% women), high social support with Class 1 features (Class

SUBMITTER: Htun HL 

PROVIDER: S-EPMC11923569 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature