Prospective associations between depression and risk of hospitalisation for infection: Findings from the UK Biobank.

ABSTRACT:

Background

Associations between depression and non-communicable disease have been well-described. However, the evidence for its role in the development of infectious disease is less understood. We aimed to examine prospective associations between depression and risk of hospitalisation for infection in middle-aged adults from the UK Biobank (linked with Hospital Episode Statistics) and assessed the role of several depression-related factors.

Methods

We assessed prospective associations between depression status at the baseline assessment (2006-2010) and hospitalisations for infection up to the end of March 2016 in 460,418 middle-aged adults enrolled in the UK Biobank (mean age = 56.23 ± 8.11 years, 53.5% female). Cox regression was used to assess associations between depressi

SUBMITTER: Ronaldson A 

PROVIDER: S-EPMC11924240 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature