Association between myosteatosis or sarcopenia based on abdominal CT and hypertension in systemic lupus erythematosus patients.

ABSTRACT:

Background

Hypertension and obesity are common in systemic lupus erythematosus (SLE) patients, with obesity-related changes potentially driving hypertension. However, the specific adiposity measures associated with hypertension in SLE patients remain unclear. This study assessed the association between myosteatosis and sarcopenia detected on abdominal CT and hypertension in SLE patients. Mediators of the association between myosteatosis and hypertension were also investigated.

Methods

This was a retrospective study involving SLE patients enrolled from January 2017 to August 2023 and who underwent abdominal CT at the L3 level to track myosteatosis and sarcopenia based on the skeletal muscle mean radiodensity (SMD) and skeletal muscle index considered as binary and continuous

SUBMITTER: Wang B 

PROVIDER: S-EPMC11924695 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature