Association between red blood cell fatty acids composition and risk of esophageal cancer: a hospital-based case-control study.

ABSTRACT:

Background

& aims: Esophageal cancer (EC) is a tumor type with high invasiveness and poor prognosis, attracting scientists' attention to its pathogenesis and etiology. Given the limited evidence and conflicting findings regarding the association between EC risk and RBC fatty acids, we aimed to evaluate this association.

Methods

The study utilized gas chromatography to analyze RBC fatty acids in 158 EC patients and 224 controls. Multivariable conditional logistic regression and restricted cubic spline analysis were employed to assess the association between EC risk and RBC fatty acids, as well as to determine the odds ratio with a 95% confidence interval (OR, 95% CI) for this association.

Results

Higher levels of total n-3 polyunsaturated fatty acids (n-3 PUFA), docosa

SUBMITTER: Yin H 

PROVIDER: S-EPMC11924718 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature