Characteristics of phase 4 clinical trials on Dental Caries registered at Clinicaltrials.gov.

ABSTRACT:

Background

Dental caries, a widespread chronic oral disease, is caused by multiple factors including microorganisms, genetic predisposition. Despite being preventable, it poses a significant global burden. This study reviews all phase 4 clinical trials on dental caries registered at ClinicalTrials.gov to provide a comprehensive overview of their characteristics.

Methods

A search was conducted on the ClinicalTrials.gov database using keywords. The registration data for all relevant phase 4 studies concerning 'Dental Caries' were retrieved. This search was conducted on the 23rd of January, 2024.

Results

The analysis included 58 phase 4 clinical trials, with most studies (67.2%) reporting complete data. The majority (63.8%) had fewer than 100 participants, and the predom

SUBMITTER: Kul KS 

PROVIDER: S-EPMC11924847 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature