Modelling the impact of the COVID-19 pandemic on cancer stage migration and excess mortality in Ireland.

ABSTRACT:

Background

Cancer treatment services were interrupted during the pandemic, which potentially increased the time to treatment initiation (TTI). This study aimed to model the impact of a hypothetical three- and six-month delay in TTI on stage of breast cancer and non-small cell lung cancer (NSCLC) in Ireland.

Methods

The distribution of cancer stage at diagnosis, net survival at one to five years post diagnosis, and projected cancer incidence for 2020 were obtained for breast cancer and NSCLC, from the National Cancer Registry Ireland. The primary outcome, the probability of an upward stage-shift from stage I to II and stage II to III, is presented with 95 % CIs.

Results

For breast cancer, the stage-shift probability after a hypothetical three-month and six-month delay

SUBMITTER: Zhang M 

PROVIDER: S-EPMC11924935 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature