Chronic Inflammatory-Related Disease and Cardiovascular Disease in MESA.

ABSTRACT:

Background

Inflammation plays a role in cardiovascular disease (CVD). We defined various noncardiovascular and noncancer conditions, both infectious and noninfectious, with a common basis of inflammation, collectively termed chronic inflammatory-related disease (ChrIRD). We describe ChrIRD and its interplay with CVD during follow-up in the Multi-Ethnic Study of Atherosclerosis.

Objectives

The aim of the study was to describe ChrIRD, its associations with CVD, and its association with mortality.

Methods

Participants were free of overt CVD at baseline with median 17.9 (Q1-Q3: 14.9-18.6) years of follow-up. ChrIRD was determined by review of hospitalization and death records of International Classification of Diseases codes. CVD diagnosis was adjudicated based on medical

SUBMITTER: Manning ES 

PROVIDER: S-EPMC11925088 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature