Frequent apheresis donation is not associated with adverse bone health in donors aged 45 years and over-Results from a cohort study in Australia.

ABSTRACT:

Background

We investigated whether frequent apheresis donors have altered risk of bone fractures, and prescription of osteoporosis medicine//s due to their repeated exposure to citrate anticoagulant.

Methods

We used the Sax Institute's 45 and Up Study data linked with blood donation and other health-related datasets. We used a "5-year qualification period" method to identify active donors who donated at least one (any type) donation in the first and fifth year of the "qualification period." We categorized donors into 0, 1-29, and 30+ donation groups based on the number of apheresis donations made during the qualification period. We then compared the risk of bone fractures, and initiation of osteoporosis medicine/s in the years following the "qualification period" between the

SUBMITTER: Karki S 

PROVIDER: S-EPMC11925129 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature