Associations Between Cognitive Impairment, Depressive Symptoms, and Work Productivity Loss in Patients With Bipolar Disorder: A Cross-Sectional Analysis.

ABSTRACT:

Aim

To evaluate the relationship between cognitive impairment and work productivity loss in patients with bipolar disorder.

Methods

We enrolled outpatients with bipolar disorder aged 18-59 years undergoing treatment and actively employed or on sick leave. Baseline demographic, medical resource use, and employment data were collected. We evaluated work productivity, cognitive impairment, quality of life (QOL), depressive symptoms (defined as a Patient Health Questionnaire-9 [PHQ-9] score of ≥ 10), and sleep disturbance. This interim analysis examined correlations among baseline symptom scores and correlations of each symptom score with work productivity loss and QOL.

Results

Among 211 participants, cognitive impairment was moderately correlated with depressive symptoms

SUBMITTER: Takaesu Y 

PROVIDER: S-EPMC11925601 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature