Bioprospecting Antarctic Microorganisms: Investigating <i>Hymenobacter psoromatis</i> PAMC26554 for Biochemical Potential.

ABSTRACT: Microorganisms from the genus Hymenobacter are known for their distinctive traits, yet their secondary metabolite (SM) production has not been thoroughly investigated. In this study, we examined the biosynthetic potential of SMs from Hymenobacter psoromatis PAMC26554, which was isolated from Antarctic lichen. In silico analysis identified biosynthetic gene clusters (BGCs) for terpenes, non-ribosomal peptide synthetases (NRPSs), and polyketide synthases (PKSs), indicating the strain's potential for novel SM production. Optimization of culture conditions showed that R2A medium at 15°C supported growth. HPLC analysis revealed phenylacetic acid (PAA) as a notable compound, which was characterized by ESI-MS and NMR, marking the first isolation of PAA from the genus Hymenobacter

SUBMITTER: Yamaguchi H 

PROVIDER: S-EPMC11925752 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature