Efficacy of combined non-invasive brain stimulation and robot-assisted gait training on lower extremity recovery post-stroke: a systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Lower extremity dysfunction post-stroke significantly impedes patient independence and quality of life. Non-invasive brain stimulation (NIBS) and robot-assisted gait training (RAGT) have individually shown promising outcomes in gait recovery. However, the synergistic efficacy of non-invasive brain stimulation combined with robot-assisted gait training remains uncertain. This systematic review and meta-analysis aim to evaluate the combined therapy's effectiveness on gait improvement and related motor functions in stroke patients.

Methods

Following PRISMA guidelines, a comprehensive search was conducted to identify randomized controlled trials (RCTs) published up to September 2024. The primary outcome was assessed using the 6-min walk test (6MWT), with secondary out

SUBMITTER: Wang J 

PROVIDER: S-EPMC11925768 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature