Geriatric nutritional risk index and body composition dictate the prognosis of elderly patients with intrahepatic cholangiocarcinoma.

ABSTRACT:

Background and aims

Malnutrition is a well-recognized predictor of poor prognosis in malignancies. Recent studies suggest that the geriatric nutritional risk index (GNRI) is a more accurate determinant of prognosis in elderly patients than conventional body mass index (BMI). This study aimed to evaluate the GNRI and body composition parameters in elderly patients with intrahepatic cholangiocarcinoma (ICC) and assess their prognostic impact on long-term outcomes.

Methods

A total of 157 elderly ICC patients (aged ≥65 years) who underwent radical resection between 2009 and 2018 were retrospectively analyzed. Skeletal muscle index (SMI), muscle attenuation (MA), visceral adipose tissue index (VATI), subcutaneous adipose tissue index (SATI), and visceral-to-subcutaneous fat ratio

SUBMITTER: Wang S 

PROVIDER: S-EPMC11925769 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature