Genome-wide associations of sweetpotato metabolites enhance genomic prediction and identify genes in metabolic and regulatory pathways.

ABSTRACT: Global sweetpotato production is increasing due to its health benefits, including high levels of complex carbohydrates and bioactive compounds. To explore the genetic basis of carbohydrates and carotenoids, we conducted a genome-wide association study (GWAS) using diverse sweetpotato accessions, two decades of phenotypic data, and 252,975 dosage-based SNPs and INDELs. Our findings confirmed a negative correlation between dry matter and β-carotene and identified interconnected metabolic pathways regulating multiple traits. Notably, phytoene synthase, involved in carotene biosynthesis, was associated with dry matter. Other pathways linked to these traits include carbohydrate metabolism, cell wall modification, phosphate starvation, stress response, and flowering regulation. To evaluate the b

SUBMITTER: Rickman TE 

PROVIDER: S-EPMC11926225 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature