Ultrasound quantitative characterization of tendinopathy with shear wave elastography in an ex vivo porcine tendon model.

ABSTRACT:

Background

Early detection and treatment of tendinopathy may prevent progression to partial tears or complete rupture. Shear wave elastography (SWE) may help address the need for better tendon pathology characterization. This study aimed to quantify the effect of structural damage in an ex vivo animal tendinopathy model using SWE.

Methods

Forty-two porcine flexor tendons were injected with a 0.05-mL bolus of 1.5% collagenase solution to induce focal structural damage without surface tears. Control tendons were injected with saline (n = 42). Twenty-one tendons from each group were incubated at 37 °C for 3.5 h, while the remaining 21 from each group were incubated for 7 h. Each group was then divided into three groups of seven, and tendon incisions were made at 25%, 50%, and 7

SUBMITTER: Steiner Q 

PROVIDER: S-EPMC11926283 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature