Determination of patient-specific trajectory for biaxially rotational dynamic-radiation therapy using a new O-ring-shaped image guided radiotherapy system.

ABSTRACT:

Background and purpose

This study developed a trajectory search method for biaxially rotational dynamic-radiation therapy (BROAD-RT) using a new O-ring-shaped linac, aimed at identifying a patient-specific trajectory in a commercial treatment planning system. Subsequently, its efficacy in the treatment of pancreatic cancer was assessed.

Materials and methods

BROAD-RT is a beam delivery technique in which the gantry and O-ring are simultaneously rotated around two axes. A beam's eye view-based structure map was generated, and the Dijkstra algorithm was then applied to explore the BROAD-RT for minimizing radiation doses to critical organs in RayStation. This procedure was evaluated in 10 patients with pancreatic cancer. For each patient, two different plans were created: volum

SUBMITTER: Hirashima H 

PROVIDER: S-EPMC11926428 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature