Comparative treatment planning of very high-energy electrons and photon volumetric modulated arc therapy: Optimising energy and beam parameters.

ABSTRACT:

Background

Very High-Energy Electron (VHEE) beams offer potential advantages over current clinical radiotherapy modalities due to their precise dose targeting and minimal peripheral dose spread, which is ideal for treating deep-seated tumours. To aid the development of clinical VHEE machines, this study adressed the need to identify optimum VHEE beam characteristics for tumours across various anatomical sites.

Materials and methods

VHEE treatment planning employed matRad, an open-source treatment planning system, by adapting its proton pencil beam scanning implementation. VHEE beam characteristics were generated using TOPAS Monte Carlo simulations. A total of 820 plans were retrospectively created and analysed across 10 pelvic and 12 thoracic cases and compared against clini

SUBMITTER: D'Andrea FS 

PROVIDER: S-EPMC11926434 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature