Efficient strategy for magnetic resonance image-guided adaptive radiotherapy of rectal cancer using a library of reference plans.

ABSTRACT:

Background and purpose

Adaptive radiotherapy for patients with rectal cancer using a magnetic resonance-guided linear accelerator has limitations in managing bladder shape variations. Conventional couch shifts may result in missing the target while requiring a large margin. Conversely, fully adaptive strategy is time-consuming. Therefore, a more efficient strategy for online adaptive radiotherapy is required.

Materials and methods

This retrospective study included 50 fractions from 10 patients with rectal cancer undergoing preoperative radiotherapy. The proposed method involved preparing a library of reference plans (LoRP) based on diverse bladder shapes. For each fraction, a plan from the LoRP was selected based on daily bladder filling. This plan was compared with those ge

SUBMITTER: Chen D 

PROVIDER: S-EPMC11926541 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature