Cancer Antigen 125 Levels at Time of Ovarian Cancer Diagnosis by Race and Ethnicity.

ABSTRACT:

Importance

International guidelines use cancer antigen (CA) 125 thresholds to recommend which patients with pelvic masses should undergo evaluation by gynecologic oncologists for ovarian cancer. However, CA-125 thresholds were developed from White populations. If CA-125 levels differ among patient populations, current guidelines may contribute to delayed ovarian cancer diagnoses among women of other races and ethnicities than White.

Objective

To examine CA-125 levels at ovarian cancer diagnosis by patient race and ethnicity and associations of elevated CA-125 levels with timely treatment.

Design, setting, and participants

This retrospective cohort study included all patients with ovarian cancer diagnosed between January 1, 2004, and December 31, 2020, using the US Nat

SUBMITTER: Smith AJB 

PROVIDER: S-EPMC11926651 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature