OCT Angiography-Derived Retinal Capillary Perfusion Measures in the Framingham Heart Study.

ABSTRACT:

Purpose

To report baseline demographic associations and novel intereye correlations of retinal perfusion in the Framingham Heart Study (FHS).

Design

Cross-sectional study.

Participants

One thousand eighteen participants were recruited. Of these, 962 participants (mean age 75 ± 7, 59% female, 1720 undilated eyes) had any OCT angiography (OCTA) data.

Methods

Participants from the community-based FHS were recruited between 2020 and 2022. Foveal-centered 3 × 3 mm² OCTA scans were used to noninvasively measure retinal capillary perfusion in both undilated eyes of each subject. Retinal capillary perfusion measures, including vessel skeleton density (VSD), vessel area density (VAD), and flux, were calculated in the superficial retinal layer, deep retinal la

SUBMITTER: Collazo Martinez AD 

PROVIDER: S-EPMC11926700 | biostudies-literature | 2025 May-Jun

REPOSITORIES: biostudies-literature